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KMID : 0359919950140040491
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Korean Journal of Nephrology
1995 Volume.14 No. 4 p.491 ~ p.495
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A Case of Mannitol-Induced Acute Renal Failure
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김미영
박용근/박철휘/장윤식/방병기
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Abstract
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Mannitol is known as metaboilcally inert alcohol and osmotic agent. It is widely used to reduce intracranial and intraocular pressure, to convert oligutic to nonoliguric ARF, and used as a diurtic agent in an attempt to prevent acute renal
failure(ARF)
in surgery. And now, it has been published that patients with underlving renal impairment are more susceptible to mannitol intoxication due to decreased excretion rate.
We report herin a case of mannitol inducedacute renal failure and intoxication occurred in a 55-year old female patient with cerebral cerebral infarction her baseline serum creatinine and BUN were normal. Mannitol was prescribed to reduce
intracranial
pressure. Mannitol induced-ARF with increased osmolal gap and clinical signs of mannitol intoxi cation were developed and treated successfully by early HD.
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KEYWORD
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